Osteopontin and oral carcinogenesis

Osteopontin and oral carcinogenesis

down-regulation of osteopontin and breast tumour progression in vivo is highly interesting [1]. Recent studies indicate a close association between not only breast cancer and osteopontin but other systemic malignancies as well. Studies over the past few years have especially shown a strong relationship between osteopontin expression and oral carcinogenesis. For instance, Devoll et al. in a rece...

HPV infection and oral carcinogenesis.

Innate Immunity and Oral Carcinogenesis

Oral cancer is initiated from stem cells of the basal layer of the epithelium that have acquired genetic alterations [2-5]. Accumulation of genetic alterations and environmental factors drive the development of tumors to highly malignant lesions, a process involving not only tumor cells but also many other non-neoplastic cells, particularly infiltrating immune cells, in the tumor microenvironme...

Preneoplasia and carcinogenesis of the oral cavity

Oral cancer, ranking sixth in the cancer incidence worldwide, is one of the most common neoplasms. Preneoplastic or premalignant (precancerous) lesions are lesions that can potentially transform into malignancy in a variety of tissues, including the oral cavity. Such oral lesions may be caused by tobacco use, exposure to the human papillomavirus and chewing of the betel nut. These substances co...

Retracted: Oral Carcinogenesis and Oral Cancer Chemoprevention: A Review

[This retracts the article DOI: 10.4061/2011/431246.].